Beilstein J. Org. Chem.2018,14, 2495–2509, doi:10.3762/bjoc.14.226
cancer cell behavior and effects of targeted chemotherapeutics with small structural differences (e.g., length of the side chain in 4Lys) was also clearly suggested.
Keywords: drug-targetingconjugates; gonadotropin-releasing hormone-III; holographic microscopy; impedimetry; short-chain fatty acids
imaging are useful and suitable techniques for the characterization of cancer cell behavior and for the evaluation of effects of drugtargetingconjugates with small structural differences (e.g., length of the side chain in 4Lys).
Based on the overall cell biological effects of [4Lys(Bu)]-GnRH-III(Dau=Aoa
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Graphical Abstract
Figure 1:
Schematic structure of Dau-conjugated GnRH-III or its derivatives containing 4Lys with acetyl or bu...